# Deconvolution

![(Left) Deconvolution. (Right) Without deconvolution](https://1268872846-files.gitbook.io/~/files/v0/b/gitbook-legacy-files/o/assets%2F-LWT7bo4Xbl2jOnmH1yB%2F-LwErId3ClHpPfNi3hRz%2F-LwEzkumJPwruk1NCBKK%2F2019-12-16%2010_24_26-Settings.png?alt=media\&token=40e8e2af-f460-4044-ab9f-90b543d38f94)

Microvolution is a 3D deconvolution implementation developed by Dr. Marc Bruce, Ph.D. of Stanford Manish Butte Lab and commercially licensed by Microvolution, LLC. This GPU-accelerated package uses Richardson-Lucy deconvolution algorithm with point-spread function (PSF) estimation optimized to best utilize GPU memory & processing architecture.

This package requires a commercial license. Microvolution jar file contains a license manager that can generate a license (.lic) file from a key. The file must be present in the same folder as the processor for activation.

[Bruce, M. A., & Butte, M. J. (2013). Real-time GPU-based 3D deconvolution. Optics express, 21(4), 4766-4773.](https://www.osapublishing.org/oe/abstract.cfm?uri=oe-21-4-4766)

[Microvolution White Paper](https://www.intelligent-imaging.com/wp-content/uploads/2019/01/DDN-Microvolution-White-Paper-V1.pdf)